fertility outcome after treatment of unruptured ectopic pregnancy with two different methotrexate protocols

Fertility Outcome after Treatment of Unruptured Ectopic Pregnancy with Two Different Methotrexate Protocols

Fertility Outcome after Treatment of Unruptured Ectopic Pregnancy with Two Different Methotrexate Protocols

BACKGROUND The purpose of this study was to compare the success rates of 70 patients from the same database, each with an ectopic pregnancy (EP) that was treated with either the single- or multi-dose methotrexate (MTX) protocols for unruptured EPs. MATERIALS AND METHODS This study was a blinded, randomized clinical trial. Treatment protocols were either single- (50 mg/m(2)) dose MTX or multi-...

comparison of two different protocols of methotrexate therapy in medical management of ectopic pregnancy

conclusions single dose therapy of mtx has sufficient power and efficacy in the treatment of ectopic pregnancy, however in patients with higher serum level of β-hcg, the successful treatment increases by using double dose method. using double dose also could decrease the necessity of operation, re-administration of mtx, and duration of hospitalization. results results showed that the rate of su...

Comparison of Two Different Protocols of Methotrexate Therapy in Medical Management of Ectopic Pregnancy

BACKGROUND Ectopic pregnancy (EP) is one of the most dangerous complications of pregnancy and without prompt diagnosis and treatment, it could become a major cause of maternal morbidity and mortality. OBJECTIVES In this randomized controlled study, we compared single and double dose of methotrexate (MTX) therapy in the treatment of ectopic pregnancy. PATIENTS AND METHODS This study was perf...

Conservative Treatment with Methotrexate of Ectopic Pregnancy

Diagnosis of ectopic pregnancy is vital, as it could save the mother’s life before uterine rupture occur. Uterine rupture accounts 6% of pregnancy related deaths and the leading cause of first trimester maternal death [2]. Diagnosis can be done by holistic approach from patient’s history, physical examination and radiology and laboratory results. The most common complaint for patients to seek f...

[Treatment of ectopic pregnancy with methotrexate].

This is a report on the successful treatment of an unruptured tubal pregnancy with methotrexate (MTX). To our knowledge eighteen cases, including ours, have been reported in Western literature so far. The advantages and drawbacks of this therapy are discussed.